A hierarchical anatomical classification schema for prediction of phenotypic side effects
Published in PLoS One, 2018
Recommended citation: Wadhwa S, Gupta A, Dokania S, Kanji R, Bagler G (2018) " A hierarchical anatomical classification schema for prediction of phenotypic side effects. " PLOS ONE. 13(3): e0193959. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193959
Prediction of adverse drug reactions is an important problem in drug discovery endeavors which can be addressed with data-driven strategies. Our study provides a strategy for hierarchical classification of side effects rooted in the anatomy and can pave the way for calibrated expert systems for multi-level prediction of side effects.
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